If you're not seeing the "USB-Serial Controller" entry when trying to use a serial connection on a mac. You probably need the missing driver:
Open the "App Store" and search for "Prolific"
β
Find, install, and open an app called "PL2303 Serial"
You'll most likely see a dialog that says it is BLOCKED.
That's ok, continue instructions below to make sure it is allowed.
β
Click "Open System Settings"
β
If you're on MacOS Sequoia:
Open the "System Settings" app from your applications.
Find "Login Items & Extensions" in the menu on the left.
Scroll to the very bottom and look for "Driver Extensions" in the "Extensions" section and click the small "β" on the right side:
Enable the toggle for PL2303Serial:
If you're on MacOS Ventura (somewhat older):
It will tell you installation was "blocked", click "Allow" and confirm with password or fingerprint.